• Describe several ways that intracellular fluid (ICF) differs from extracellular fluid (ECF). What ions are higher in the ICF vs ECF? '

K+ are higher concentration in ECF

• Describe what a concentration gradient is and how it leads to diffusion and the establishment of a dynamic equilibrium.
  Can you identify the flow of ions in/out of cells based on concentration gradients?
• Describe the mechanism of the Na+/K+ pump and explain how it contributes to the resting membrane potential of a cell.
  • What would happen to the resting membrane potential if the Na+/K+ pump was mutated and not working?
• Describe the mechanism of Na+ and K+ leak channels. How do they contribute to the resting membrane potential of a cell? How do they contribute to membrane permeability?
• What is the resting membrane potential? What voltage value is it typically for most cells in your body?